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Missouri Medical Marijuana Qualifying Conditions

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Official Missouri List

Missouri Approved Qualifying Conditions

Browse 24 approved conditions. Conditions with an MMJ.com guide are clickable.

What conditions qualify for medical marijuana in Missouri?

Missouri allows medical marijuana for any chronic, debilitating condition a physician believes would benefit from cannabis treatment. This includes chronic pain, PTSD, cancer, epilepsy, anxiety, migraines, and more. MMJ.com offers telehealth evaluations for $149.99 with same-day certification and a 100% money-back guarantee.

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What is the complete list of Missouri qualifying conditions?

Missouri's Medical Marijuana Program, administered by the Department of Health and Senior Services (DHSS), has one of the most patient-friendly qualifying criteria in the country. Physicians can recommend cannabis for:

Specifically Listed Conditions

  • Cancer
  • Epilepsy and Seizure Disorders
  • Glaucoma
  • Intractable Migraines
  • Chronic Pain
  • Severe Muscle Spasms (including Multiple Sclerosis)
  • Parkinson's Disease
  • Post-Traumatic Stress Disorder (PTSD)
  • HIV/AIDS
  • Hepatitis C
  • Amyotrophic Lateral Sclerosis (ALS)
  • Crohn's Disease
  • Ulcerative Colitis
  • Alzheimer's Disease (with agitation)
  • Huntington's Disease
  • Autism Spectrum Disorder
  • Terminal Illness

Physician Discretion Clause

Any chronic, debilitating, or other medical condition that a physician determines medical marijuana could benefit—including:

  • Anxiety
  • Depression
  • Insomnia
  • Fibromyalgia
  • Neuropathy
  • Arthritis
  • And many more

This makes Missouri's program one of the most accessible in the nation.

Why get a medical card when Missouri has recreational marijuana?

Missouri legalized recreational marijuana in November 2022, but medical cards provide significant advantages:

BenefitMedical CardRecreational
Minimum Age18+21+
Sales Tax4%6%
Possession LimitHigher limits3 oz
Home Cultivation6 plants6 plants (w/license)
Purchase PriorityYesNo

Save Money: Medical patients pay 4% sales tax vs. 6% recreational. On $300/month in purchases, that's $72/year in savings.

How do I qualify for a Missouri medical marijuana card?

To qualify for medical marijuana in Missouri, you must:

  1. Be a Missouri resident with valid state ID
  2. Have a qualifying condition (or condition your doctor believes would benefit)
  3. Complete a physician evaluation (telehealth evaluations are legal in Missouri)
  4. Register with DHSS and pay the state fee
  5. Receive your card and begin purchasing at dispensaries

MMJ.com connects you with Missouri-licensed physicians for a 10-15 minute telehealth evaluation. Most patients receive same-day certification.

How much does a Missouri medical marijuana card cost?

Fee TypeCost
Physician Evaluation (MMJ.com)$149.99
State Registration Fee (3 years)$25
Total Cost$174.99

Missouri now offers 3-year medical marijuana cards for just $25—one of the lowest state fees in the country. MMJ.com provides a 100% money-back guarantee if you're not approved.

Can I grow marijuana at home in Missouri?

Yes! Missouri allows home cultivation for medical marijuana patients:

  • Up to 6 flowering plants per patient
  • Up to 6 additional plants for registered caregivers
  • Maximum 18 plants per household
  • Must be grown in an enclosed, locked facility
  • Plants must not be visible from public areas

About the Qualifying Medical Conditions

Below is information about each qualifying condition and the research that informed Missouri's decision to include it in the state program.

Chronic Pain, Migraines, and Muscle Spasms

Chronic pain, intractable migraines, and muscle spasms are approved qualifying conditions under Missouri's medical marijuana program. Missouri included these conditions based on systematic reviews examining cannabinoid use among patients with chronic pain conditions. (Whiting et al., JAMA 2015) (Rhyne et al., Pharmacotherapy 2016)

PTSD

PTSD is an approved qualifying condition under Missouri's medical marijuana program. Missouri included this condition based on research examining cannabinoid use among patients with PTSD. (Roitman et al., J Clin Psychopharmacol 2014)

Epilepsy and Seizure Disorders

Seizure disorders, including epilepsy, are approved qualifying conditions under Missouri's medical marijuana program. Missouri included these conditions based on clinical trial research examining CBD in patients with treatment-resistant epilepsy. (Devinsky et al., NEJM 2017)

Cancer, HIV/AIDS, and Terminal Illness

These are approved qualifying conditions under Missouri's medical marijuana program. Missouri included these conditions based on research examining cannabinoid use among patients experiencing treatment-related symptoms or end-of-life care needs. (Whiting et al., JAMA 2015) (Woolridge et al., J Pain Symptom Manage 2005)

Multiple Sclerosis

MS is an approved qualifying condition under Missouri's medical marijuana program. Missouri included this condition based on clinical research examining cannabinoid use in patients with MS-related spasticity. (Zajicek et al., J Neurol Neurosurg Psychiatry 2012)

Parkinson's Disease

Parkinson's Disease is an approved qualifying condition under Missouri's medical marijuana program. Missouri included this condition based on research examining cannabinoid use among Parkinson's patients. (Lotan et al., Clin Neuropharmacol 2014)

Huntington's Disease

Huntington's Disease is an approved qualifying condition under Missouri's medical marijuana program. Missouri included this condition based on research examining cannabinoid use in patients with neurodegenerative conditions.

Crohn's Disease and Ulcerative Colitis

Inflammatory bowel diseases are approved qualifying conditions under Missouri's medical marijuana program. Missouri included these conditions based on clinical research examining cannabis use in IBD patients. (Naftali et al., Clin Gastroenterol Hepatol 2013)

Autism Spectrum Disorder

Autism Spectrum Disorder is an approved qualifying condition under Missouri's medical marijuana program. Missouri included this condition based on research examining cannabis use among patients with autism spectrum disorder. (Aran et al., Sci Rep 2019)

Glaucoma

Glaucoma is an approved qualifying condition under Missouri's medical marijuana program. Missouri included this condition based on early research examining the relationship between cannabinoids and intraocular pressure. (Hepler & Frank, JAMA 1971)

Hepatitis C

Hepatitis C is an approved qualifying condition under Missouri's medical marijuana program. Missouri included this condition based on research examining cannabis use among patients undergoing antiviral treatment. (Sylvestre et al., Eur J Gastroenterol Hepatol 2006)

ALS

ALS is an approved qualifying condition under Missouri's medical marijuana program. Missouri included this condition based on research surveying ALS patients about symptom management. (Carter et al., Am J Hosp Palliat Care 2010)

Alzheimer's Disease

Alzheimer's Disease (with agitation) is an approved qualifying condition under Missouri's medical marijuana program. Missouri included this condition based on research examining cannabinoid use in dementia patients. (Woodward et al., J Alzheimers Dis 2014)

Physician Discretion Conditions

Missouri's physician discretion clause allows doctors to recommend medical marijuana for any condition they believe would benefit. This is based on Missouri statute and does not require specific research citations for each condition.

How do caregivers and pediatric patients qualify?

Caregiver Requirements

  • Must be at least 21 years old
  • Complete background check
  • Register with DHSS ($25 fee)
  • Can cultivate 6 additional plants for patient
  • Can assist one or more qualified patients

Pediatric Patient Requirements

  • Must have a qualifying condition
  • Requires certification from two licensed healthcare providers
  • Parent or legal guardian must consent and serve as caregiver
  • MMJ.com provides specialized guidance for families

Can I petition for a new qualifying condition in Missouri?

Yes, Missouri residents can petition DHSS to add new conditions to the officially listed qualifying conditions. However, due to the physician discretion clause, most debilitating conditions can already be approved by a recommending physician.

Petitions require:

  • Detailed medical evidence
  • Scientific studies supporting cannabis treatment
  • Healthcare professional endorsements

Frequently Asked Questions

How long does it take to get a medical marijuana card in Missouri?

The telehealth evaluation takes 10-15 minutes with same-day certification. DHSS processes applications within 30 days, though most approvals come within 1-2 weeks. Your card is valid for 3 years.

Can out-of-state patients access Missouri's medical marijuana program?

No, only Missouri residents can participate in the state's medical marijuana program. You must have a valid Missouri state ID or driver's license.

Does anxiety qualify for medical marijuana in Missouri?

Yes! Missouri's physician discretion clause allows doctors to recommend medical marijuana for any condition they believe would benefit, including anxiety. Consult with an MMJ.com physician to discuss your symptoms.

Can I use telehealth for my Missouri medical marijuana evaluation?

Yes, Missouri allows telehealth evaluations for medical marijuana certifications. MMJ.com offers secure, HIPAA-compliant video consultations with Missouri-licensed physicians.

What documents do I need for my evaluation?

You'll need a valid Missouri ID. Medical records are helpful but not required—Missouri physicians can recommend cannabis based on their evaluation of your symptoms.

How long does a Missouri medical marijuana card last?

Missouri medical marijuana cards are now valid for 3 years. The state registration fee is $25 for the full 3-year term.

How much marijuana can I possess with a Missouri medical card?

Medical patients can possess a higher amount than recreational users. Specific limits are determined by your physician's recommendation, but generally exceed the recreational 3-ounce limit.

What is the approval rate for Missouri medical marijuana evaluations?

MMJ.com maintains a 98% approval rate for qualified patients. If you're not approved, you receive a full refund under our 100% money-back guarantee.

Where can I purchase medical marijuana in Missouri?

Missouri has over 200 licensed dispensaries statewide. Medical patients can shop at any licensed dispensary with their valid medical card.

Medical Disclaimer

This page provides information about Missouri's qualifying conditions for medical cannabis. The inclusion of a condition in Missouri's program does not constitute medical advice or a guarantee of therapeutic benefit. Individual results vary. Potential side effects may include dizziness, sedation, and cognitive changes. Always consult a healthcare provider before starting treatment.


Reviewed by MMJ.com Medical Advisory Team Last Updated: December 17, 2025

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FAQ

Common Questions About Missouri MMJ Cards

What conditions qualify for medical marijuana in Missouri?+
Missouri allows medical marijuana for ANY chronic or debilitating condition a physician believes would benefit from cannabis. This includes chronic pain, PTSD, anxiety, cancer, epilepsy, migraines, depression, insomnia, and many more conditions.
How long does it take to get a medical marijuana card in Missouri?+
The telehealth evaluation takes 10-15 minutes with same-day certification. DHSS processes applications within 30 days, though most approvals come within 1-2 weeks. Your card is valid for 3 years.
How much does a Missouri medical marijuana card cost?+
A Missouri medical marijuana card costs $149.99 for the physician evaluation through MMJ.com, plus $25 for a 3-year state registration. Total cost is $174.99. MMJ.com offers a 100% money-back guarantee.
Why get a medical card if Missouri has recreational marijuana?+
Medical patients pay only 4% tax (vs. 6% recreational), can be 18+ (vs. 21+), have higher possession limits, and get purchase priority. On $300/month in purchases, you save $72/year in taxes alone.
Can I grow marijuana at home in Missouri?+
Yes, Missouri allows medical patients to cultivate up to 6 flowering plants. Caregivers can grow 6 additional plants for their patient. Plants must be in an enclosed, locked facility not visible from public areas.
Does anxiety qualify for medical marijuana in Missouri?+
Yes! Missouri's physician discretion clause allows doctors to recommend medical marijuana for any debilitating condition, including anxiety, depression, and insomnia. Consult with an MMJ.com physician.
Can I use telehealth for my Missouri medical marijuana evaluation?+
Yes, Missouri allows telehealth evaluations for medical marijuana certifications. MMJ.com offers HIPAA-compliant video consultations with Missouri-licensed physicians. The process takes 10-15 minutes from home.
Can out-of-state patients access Missouri's medical marijuana program?+
No, only Missouri residents can participate in the state's medical marijuana program. You must have a valid Missouri state ID or driver's license to register.
How long does a Missouri medical marijuana card last?+
Missouri medical marijuana cards are valid for 3 years. The state registration fee is $25 for the full 3-year term—one of the lowest fees in the country.
What is the approval rate for Missouri medical marijuana evaluations?+
MMJ.com maintains a 98% approval rate for qualified Missouri patients. If you're not approved by our physician, you receive a full refund under our 100% money-back guarantee.

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Last Updated: December 17, 2025 · Reviewed by MMJ.com Medical Advisory Team