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Missouri Medical Marijuana Qualifying Conditions

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No appointments needed. No waiting rooms. Just fast, professional medical evaluations from home.

01

Complete Registration

Fill out our secure intake form with your medical history. Takes about 5 minutes.

02

Phone or Video Call

Connect with a licensed Missouri physician via phone or video. Your choice!

03

Get Certified

Receive your certification instantly. Register with the state to get your card.

Why MMJ.com?

The Trusted Choice for Missouri Patients

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If you're not approved, you get a full refund. No questions asked.

State-Licensed Physicians

All our doctors are licensed to practice in Missouri and specialize in cannabis medicine.

Same-Day Certifications

Most patients receive their certification within hours of their evaluation.

Phone or Video—Your Choice

Missouri allows telehealth evaluations via phone call or video chat. You choose!

24/7 Support

Our patient care team is available around the clock to answer your questions.

Easy Renewals

When your card expires, renewing is even easier than the first time.

Official Missouri List

Missouri Approved Qualifying Conditions

Browse 24 approved conditions. Conditions with an MMJ.com guide are clickable.

What conditions qualify for medical marijuana in Missouri?

Missouri allows medical marijuana for any chronic, debilitating condition a physician believes would benefit from cannabis treatment. This includes chronic pain, PTSD, cancer, epilepsy, anxiety, migraines, and more. MMJ.com offers telehealth evaluations for $149.99 with same-day certification and a 100% money-back guarantee.

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What is the complete list of Missouri qualifying conditions?

Missouri's Medical Marijuana Program, administered by the Department of Health and Senior Services (DHSS), has one of the most patient-friendly qualifying criteria in the country. Physicians can recommend cannabis for:

Specifically Listed Conditions

  • Cancer
  • Epilepsy and Seizure Disorders
  • Glaucoma
  • Intractable Migraines
  • Chronic Pain
  • Severe Muscle Spasms (including Multiple Sclerosis)
  • Parkinson's Disease
  • Post-Traumatic Stress Disorder (PTSD)
  • HIV/AIDS
  • Hepatitis C
  • Amyotrophic Lateral Sclerosis (ALS)
  • Crohn's Disease
  • Ulcerative Colitis
  • Alzheimer's Disease (with agitation)
  • Huntington's Disease
  • Autism Spectrum Disorder
  • Terminal Illness

Physician Discretion Clause

Any chronic, debilitating, or other medical condition that a physician determines medical marijuana could benefit—including:

  • Anxiety
  • Depression
  • Insomnia
  • Fibromyalgia
  • Neuropathy
  • Arthritis
  • And many more

This makes Missouri's program one of the most accessible in the nation.

Why get a medical card when Missouri has recreational marijuana?

Missouri legalized recreational marijuana in November 2022, but medical cards provide significant advantages:

BenefitMedical CardRecreational
Minimum Age18+21+
Sales Tax4%6%
Possession LimitHigher limits3 oz
Home Cultivation6 plants6 plants (w/license)
Purchase PriorityYesNo

Save Money: Medical patients pay 4% sales tax vs. 6% recreational. On $300/month in purchases, that's $72/year in savings.

How do I qualify for a Missouri medical marijuana card?

To qualify for medical marijuana in Missouri, you must:

  1. Be a Missouri resident with valid state ID
  2. Have a qualifying condition (or condition your doctor believes would benefit)
  3. Complete a physician evaluation (telehealth evaluations are legal in Missouri)
  4. Register with DHSS and pay the state fee
  5. Receive your card and begin purchasing at dispensaries

MMJ.com connects you with Missouri-licensed physicians for a 10-15 minute telehealth evaluation. Most patients receive same-day certification.

How much does a Missouri medical marijuana card cost?

Fee TypeCost
Physician Evaluation (MMJ.com)$149.99
State Registration Fee (3 years)$25
Total Cost$174.99

Missouri now offers 3-year medical marijuana cards for just $25—one of the lowest state fees in the country. MMJ.com provides a 100% money-back guarantee if you're not approved.

Can I grow marijuana at home in Missouri?

Yes! Missouri allows home cultivation for medical marijuana patients:

  • Up to 6 flowering plants per patient
  • Up to 6 additional plants for registered caregivers
  • Maximum 18 plants per household
  • Must be grown in an enclosed, locked facility
  • Plants must not be visible from public areas

What are the benefits of medical marijuana for each condition?

Chronic Pain, Migraines, and Muscle Spasms

Therapeutic Benefits: Reduces chronic pain intensity, migraine frequency, and muscle spasticity.

Research Evidence: Studies show cannabis effectively manages chronic pain with fewer side effects than opioids and reduces migraine frequency by up to 50%.

PTSD and Anxiety

Therapeutic Benefits: Reduces anxiety, nightmares, insomnia, and other trauma-related symptoms.

Research Evidence: Clinical research demonstrates significant improvements in sleep quality, anxiety reduction, and emotional stability.

Epilepsy and Seizure Disorders

Therapeutic Benefits: Reduces seizure frequency and severity.

Research Evidence: FDA-approved CBD (Epidiolex) has demonstrated significant effectiveness in controlling severe seizure disorders.

Cancer, HIV/AIDS, and Terminal Illness

Therapeutic Benefits: Alleviates chemotherapy-induced nausea, chronic pain, appetite loss, and provides comfort during treatment.

Research Evidence: Clinical trials confirm cannabinoids effectively reduce nausea and stimulate appetite.

Parkinson's and Huntington's Disease

Therapeutic Benefits: Manages tremors, motor control issues, and improves quality of life.

Research Evidence: Early research shows cannabis's potential in improving motor symptoms and reducing involuntary movements.

Crohn's Disease and Ulcerative Colitis

Therapeutic Benefits: Reduces inflammation, pain, and gastrointestinal discomfort.

Research Evidence: Clinical evidence supports cannabis use in managing inflammatory bowel conditions.

Autism Spectrum Disorder

Therapeutic Benefits: May reduce behavioral issues, anxiety, and aggression; may improve communication.

Research Evidence: Emerging research shows promising results for symptom management.

How do caregivers and pediatric patients qualify?

Caregiver Requirements

  • Must be at least 21 years old
  • Complete background check
  • Register with DHSS ($25 fee)
  • Can cultivate 6 additional plants for patient
  • Can assist one or more qualified patients

Pediatric Patient Requirements

  • Must have a qualifying condition
  • Requires certification from two licensed healthcare providers
  • Parent or legal guardian must consent and serve as caregiver
  • MMJ.com provides specialized guidance for families

Can I petition for a new qualifying condition in Missouri?

Yes, Missouri residents can petition DHSS to add new conditions to the officially listed qualifying conditions. However, due to the physician discretion clause, most debilitating conditions can already be approved by a recommending physician.

Petitions require:

  • Detailed medical evidence
  • Scientific studies supporting cannabis treatment
  • Healthcare professional endorsements

Frequently Asked Questions

How long does it take to get a medical marijuana card in Missouri?

The telehealth evaluation takes 10-15 minutes with same-day certification. DHSS processes applications within 30 days, though most approvals come within 1-2 weeks. Your card is valid for 3 years.

Can out-of-state patients access Missouri's medical marijuana program?

No, only Missouri residents can participate in the state's medical marijuana program. You must have a valid Missouri state ID or driver's license.

Does anxiety qualify for medical marijuana in Missouri?

Yes! Missouri's physician discretion clause allows doctors to recommend medical marijuana for any condition they believe would benefit, including anxiety. Consult with an MMJ.com physician to discuss your symptoms.

Can I use telehealth for my Missouri medical marijuana evaluation?

Yes, Missouri allows telehealth evaluations for medical marijuana certifications. MMJ.com offers secure, HIPAA-compliant video consultations with Missouri-licensed physicians.

What documents do I need for my evaluation?

You'll need a valid Missouri ID. Medical records are helpful but not required—Missouri physicians can recommend cannabis based on their evaluation of your symptoms.

How long does a Missouri medical marijuana card last?

Missouri medical marijuana cards are now valid for 3 years. The state registration fee is $25 for the full 3-year term.

How much marijuana can I possess with a Missouri medical card?

Medical patients can possess a higher amount than recreational users. Specific limits are determined by your physician's recommendation, but generally exceed the recreational 3-ounce limit.

What is the approval rate for Missouri medical marijuana evaluations?

MMJ.com maintains a 98% approval rate for qualified patients. If you're not approved, you receive a full refund under our 100% money-back guarantee.

Where can I purchase medical marijuana in Missouri?

Missouri has over 200 licensed dispensaries statewide. Medical patients can shop at any licensed dispensary with their valid medical card.

Medical Disclaimer

Medical cannabis effects and effectiveness vary among individuals. Potential side effects include dizziness, sedation, cognitive impairment, and risk of dependency. Always consult a qualified healthcare provider before beginning treatment.


Reviewed by MMJ.com Medical Advisory Team Last Updated: December 17, 2025

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FAQ

Common Questions About Missouri MMJ Cards

What conditions qualify for medical marijuana in Missouri?+
Missouri allows medical marijuana for ANY chronic or debilitating condition a physician believes would benefit from cannabis. This includes chronic pain, PTSD, anxiety, cancer, epilepsy, migraines, depression, insomnia, and many more conditions.
How long does it take to get a medical marijuana card in Missouri?+
The telehealth evaluation takes 10-15 minutes with same-day certification. DHSS processes applications within 30 days, though most approvals come within 1-2 weeks. Your card is valid for 3 years.
How much does a Missouri medical marijuana card cost?+
A Missouri medical marijuana card costs $149.99 for the physician evaluation through MMJ.com, plus $25 for a 3-year state registration. Total cost is $174.99. MMJ.com offers a 100% money-back guarantee.
Why get a medical card if Missouri has recreational marijuana?+
Medical patients pay only 4% tax (vs. 6% recreational), can be 18+ (vs. 21+), have higher possession limits, and get purchase priority. On $300/month in purchases, you save $72/year in taxes alone.
Can I grow marijuana at home in Missouri?+
Yes, Missouri allows medical patients to cultivate up to 6 flowering plants. Caregivers can grow 6 additional plants for their patient. Plants must be in an enclosed, locked facility not visible from public areas.
Does anxiety qualify for medical marijuana in Missouri?+
Yes! Missouri's physician discretion clause allows doctors to recommend medical marijuana for any debilitating condition, including anxiety, depression, and insomnia. Consult with an MMJ.com physician.
Can I use telehealth for my Missouri medical marijuana evaluation?+
Yes, Missouri allows telehealth evaluations for medical marijuana certifications. MMJ.com offers HIPAA-compliant video consultations with Missouri-licensed physicians. The process takes 10-15 minutes from home.
Can out-of-state patients access Missouri's medical marijuana program?+
No, only Missouri residents can participate in the state's medical marijuana program. You must have a valid Missouri state ID or driver's license to register.
How long does a Missouri medical marijuana card last?+
Missouri medical marijuana cards are valid for 3 years. The state registration fee is $25 for the full 3-year term—one of the lowest fees in the country.
What is the approval rate for Missouri medical marijuana evaluations?+
MMJ.com maintains a 98% approval rate for qualified Missouri patients. If you're not approved by our physician, you receive a full refund under our 100% money-back guarantee.

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Last Updated: December 17, 2025 · Reviewed by MMJ.com Medical Advisory Team