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Root 66 Dispensary | Saint Louis, MO Dispensary

Medical Marijuana Dispensary in Saint Louis, Missouri

3737 S GRAND BLVD, Saint Louis, MO 63118

Save 6% at Root 66 Dispensary

Medical cardholders pay less tax than recreational buyers

Get Your MO Card

Where is Root 66 Dispensary located?

Address

3737 S GRAND BLVD

Saint Louis, MO 63118

Get Directions

Hours

9am-9pm Daily

Services Available

Medical SalesRecreational SalesDeliveryCurbside Pickup

📋Root 66 Dispensary Menu - Price Guide

Saint Louis, Missouri • Expected pricing by product category

Flower(1g)
$8 – $15
Pre-Rolls(each)
$8 – $40
Edibles(100mg)
$15 – $35
Concentrates(1g)
$30 – $60
Vape Cartridges(cart)
$25 – $75
Tinctures & Oils(bottle)
$35 – $70
Topicals(item)
$25 – $55
Capsules & Pills(bottle)
$35 – $65

Medical Card Holders Save 2% on Taxes

Recreational: ~10.2% tax • Medical: ~8.2% tax

Save 2% on taxes. Missouri is a low-tax cannabis state.

Prices based on Missouri dispensary averages. Actual prices vary by location, availability, and current promotions.

Last updated: January 2026 •View detailed Missouri pricing →

What do I need to shop at Root 66 Dispensary?

Valid Missouri Medical Marijuana Card

Required for medical purchases. Card must be current and unexpired.

Government-Issued Photo ID

Driver's license, state ID, or passport. Must match card information.

21+ for Recreational (No Card Needed)

Adults 21+ can purchase recreational cannabis with valid ID, but pay 10.25% tax.

Cash or Debit Recommended

Most dispensaries accept cash and debit. ATMs typically available on-site.

Don't have a Missouri medical card?

Get certified online in minutes. Same-day telehealth appointments available.

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How much can I save with a medical card at Root 66 Dispensary?

Missouri charges different tax rates for medical and recreational cannabis. Medical cardholders save significantly on every purchase.

Medical (With Card)

4.225%

Total tax rate

Recreational (No Card)

10.25%

Total tax rate

Example Savings on $100 Purchase:

Medical tax:$4.22
Recreational tax:$10.25
You save:$6.03

Is Root 66 Dispensary a licensed dispensary?

State License Number

DIS000003

Verify at Missouri Department of Health

Frequently Asked Questions About Root 66 Dispensary

Where is Root 66 Dispensary located?

Root 66 Dispensary is located at 3737 S GRAND BLVD, Saint Louis, MO 63118. You can reach them at (636) 262-4163.

What are Root 66 Dispensary's hours of operation?

Root 66 Dispensary is open 9am-9pm Daily. Hours may vary on holidays, so we recommend calling ahead.

Does Root 66 Dispensary accept credit cards?

Root 66 Dispensary accepts cash and debit cards. Most dispensaries have an ATM on-site for your convenience. Contact them directly for specific payment options.

Do I need a medical card to shop at Root 66 Dispensary?

Root 66 Dispensary serves both medical and recreational customers. Medical cardholders enjoy 6% tax savings compared to recreational purchases. Adults 21+ can purchase recreational cannabis with valid ID.

Does Root 66 Dispensary offer delivery?

Yes, Root 66 Dispensary offers delivery services. Contact them or visit their website to check delivery availability in your area and place an order.

Get Your Missouri Card

Required for medical purchases at Root 66 Dispensary

  • $149 doctor evaluation
  • $25 state fee
  • Valid for 3 years
  • 100% money-back guarantee
Schedule Evaluation

Missouri Resources

Nearby Dispensaries

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Ready to Visit Root 66 Dispensary?

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Medically Reviewed by Dr. Kevin Kargman, DO (License #2022027983)

Reviewed: December 31, 2025 • Research Standards

Last Updated: December 2025 · Reviewed by Dr. Kevin Kargman, DO