MMJ.com
MedicalRecreationalLicensed

Root 66 Wellness | Des Peres, MO Dispensary

Medical Marijuana Dispensary in Des Peres, Missouri

12095 MANCHESTER RD, Des Peres, MO 63131

Save 6% at Root 66 Wellness

Medical cardholders pay less tax than recreational buyers

Get Your MO Card

Where is Root 66 Wellness located?

Address

12095 MANCHESTER RD

Des Peres, MO 63131

Get Directions

Hours

9am-9pm Daily

Services Available

Medical SalesRecreational SalesDeliveryCurbside Pickup

📋Root 66 Wellness Menu - Price Guide

Des Peres, Missouri • Expected pricing by product category

Flower(1g)
$8 – $15
Pre-Rolls(each)
$8 – $40
Edibles(100mg)
$15 – $35
Concentrates(1g)
$30 – $60
Vape Cartridges(cart)
$25 – $75
Tinctures & Oils(bottle)
$35 – $70
Topicals(item)
$25 – $55
Capsules & Pills(bottle)
$35 – $65

Medical Card Holders Save 2% on Taxes

Recreational: ~10.2% tax • Medical: ~8.2% tax

Save 2% on taxes. Missouri is a low-tax cannabis state.

Prices based on Missouri dispensary averages. Actual prices vary by location, availability, and current promotions.

Last updated: January 2026 •View detailed Missouri pricing →

What do I need to shop at Root 66 Wellness?

Valid Missouri Medical Marijuana Card

Required for medical purchases. Card must be current and unexpired.

Government-Issued Photo ID

Driver's license, state ID, or passport. Must match card information.

21+ for Recreational (No Card Needed)

Adults 21+ can purchase recreational cannabis with valid ID, but pay 10.25% tax.

Cash or Debit Recommended

Most dispensaries accept cash and debit. ATMs typically available on-site.

Don't have a Missouri medical card?

Get certified online in minutes. Same-day telehealth appointments available.

Get Your Medical Card

How much can I save with a medical card at Root 66 Wellness?

Missouri charges different tax rates for medical and recreational cannabis. Medical cardholders save significantly on every purchase.

Medical (With Card)

4.225%

Total tax rate

Recreational (No Card)

10.25%

Total tax rate

Example Savings on $100 Purchase:

Medical tax:$4.22
Recreational tax:$10.25
You save:$6.03

Is Root 66 Wellness a licensed dispensary?

State License Number

DIS000202

Verify at Missouri Department of Health

Frequently Asked Questions About Root 66 Wellness

Where is Root 66 Wellness located?

Root 66 Wellness is located at 12095 MANCHESTER RD, Des Peres, MO 63131. You can reach them at (636) 262-4163.

What are Root 66 Wellness's hours of operation?

Root 66 Wellness is open 9am-9pm Daily. Hours may vary on holidays, so we recommend calling ahead.

Does Root 66 Wellness accept credit cards?

Root 66 Wellness accepts cash and debit cards. Most dispensaries have an ATM on-site for your convenience. Contact them directly for specific payment options.

Do I need a medical card to shop at Root 66 Wellness?

Root 66 Wellness serves both medical and recreational customers. Medical cardholders enjoy 6% tax savings compared to recreational purchases. Adults 21+ can purchase recreational cannabis with valid ID.

Does Root 66 Wellness offer delivery?

Yes, Root 66 Wellness offers delivery services. Contact them or visit their website to check delivery availability in your area and place an order.

Get Your Missouri Card

Required for medical purchases at Root 66 Wellness

  • $149 doctor evaluation
  • $25 state fee
  • Valid for 3 years
  • 100% money-back guarantee
Schedule Evaluation

Missouri Resources

Nearby Dispensaries

View All Missouri Dispensaries

Ready to Visit Root 66 Wellness?

Get your Missouri medical marijuana card online. Same-day telehealth appointments available.

Get Your MO Medical Card

Medically Reviewed by Dr. Kevin Kargman, DO (License #2022027983)

Reviewed: December 31, 2025 • Research Standards

Last Updated: December 2025 · Reviewed by Dr. Kevin Kargman, DO