Medical Cannabis and Driving: What Patients Must Know

What Researchers Found About and Cannabis

Updated January 24, 2026Australian Journal of General Practice, 2021

The Study at a Glance

Inconclusive

Published

Australian Journal of General Practice, 2021

Researchers

University of Sydney (Australia)

Study Type

Systematic Review

Key Finding

THC impairs driving performance and increases crash risk, with effects lasting 8 hours or more with oral products. Patients should avoid driving during treatment initiation and for several hours or more after each dose.

Key Finding: THC impairs driving performance and increases crash risk, with effects lasting 8 hours or more with oral products. Patients should avoid driving during treatment initiation and for several hours or more after each dose.

What Researchers Studied About This Condition and Cannabis

As medical cannabis use increases, patients need clear guidance on a critical safety question: Can I drive while using medical cannabis?

This 2021 review from Australia examines the scientific evidence on cannabis and driving impairment, providing practical guidance for patients and physicians.

The review addresses both THC and CBD products, and importantly discusses the legal implications of medical cannabis use for driving.

How This Systematic Review Was Conducted

Researchers reviewed the scientific literature on cannabis and driving:

• Examined evidence on THC driving impairment • Assessed crash risk data • Reviewed how long impairment lasts • Discussed legal implications and drug testing

This Condition Treatment Results

The Main Results:

  • 1THC impairs driving performance and increases crash risk
  • 2Effects are more pronounced in occasional (vs regular) users
  • 3Oral cannabis impairment can last 8 HOURS OR MORE
  • 4Patients may test positive even when not feeling impaired
  • 5Medical cannabis does NOT exempt from roadside drug testing

By the Numbers

StatisticWhat It Means
8+ hoursimpairment can last with oral products
Not exemptmedical cannabis users from drug testing
Higher riskfor occasional vs regular users
Avoiddriving during treatment initiation
8+ hours

impairment can last with oral products

Not exempt

medical cannabis users from drug testing

Higher risk

for occasional vs regular users

Avoid

driving during treatment initiation

What This Means for This Condition Patients

This review provides critical safety information for medical cannabis patients:

THC and driving - the key facts: • THC DOES impair driving—this is well-established • THC increases crash risk • Effects last longer than you might think: 8 HOURS OR MORE with oral products • Occasional users are MORE impaired than regular users at the same dose

Critical legal issues: • Medical cannabis does NOT exempt you from roadside drug testing • You can test positive for THC even when you don't feel impaired • "Medical necessity" is generally not a legal defense

Safety recommendations: • Avoid driving during treatment initiation when effects are unpredictable • Don't drive for several hours or more after each dose • With oral cannabis products, impairment can last 8 hours or more • Plan transportation accordingly—don't assume you're safe to drive

Quick Answers: This Condition and Cannabis

Direct answers based on the findings of this study:

Research Summary: Answers are based on published peer-reviewed studies and represent research findings, not medical recommendations. Individual results may vary. Always consult a healthcare provider before making treatment decisions.

Can I drive high on weed?

No—cannabis impairs driving and increases crash risk. Wait at least several hours after using. With edibles, impairment can last 8+ hours. Plan a ride or don't use if you need to drive.

Source: McGregor et al., Australian Journal of General Practice, 2021 (PMID: 34059836)

How long after smoking weed can I drive?

Wait several hours or more—edibles can impair you 8+ hours. Occasional users are MORE impaired than regular users at the same dose. When starting medical cannabis, don't drive until you know how it affects you.

Source: McGregor et al., Australian Journal of General Practice, 2021 (PMID: 34059836)

Can I get a DUI with a medical marijuana card?

Yes. A medical card does NOT protect you from DUI charges. You can test positive for THC even when you don't feel high, and "I have a prescription" is not a legal defense in most places.

Source: McGregor et al., Australian Journal of General Practice, 2021 (PMID: 34059836)

This is educational content, not medical advice

The research summarized here is for informational purposes only. Individual results may vary, and what works in studies may not work the same way for everyone. Always consult with a qualified healthcare provider before making changes to your treatment plan or starting medical cannabis therapy.

Important Limitations

This study has some caveats to keep in mind when interpreting the results:

  • Review focused on Australian legal context
  • Individual impairment varies significantly
  • Limited research on long-term medical cannabis users
  • Drug testing methods vary by jurisdiction
  • Legal landscape is rapidly evolving

The Bottom Line on Cannabis for This Condition

This review delivers essential safety guidance for medical cannabis patients: Cannabis impairs driving and increases crash risk, with effects lasting 8 hours or more with oral products. Patients should not drive during treatment initiation or for several hours or more after each dose. Importantly, having a medical cannabis prescription does NOT exempt patients from roadside drug testing. Plan your transportation accordingly—these findings are critical for any patient using medical cannabis who needs to drive.

Do You Qualify for Medical Marijuana?

If you're living with qualifying condition, you may qualify for a medical marijuana card. Our licensed physicians can evaluate you from home via telehealth.

Related Research & Resources

Source

Arkell TR, McCartney D, McGregor IS "Medical cannabis and driving" Australian Journal of General Practice. 2021. DOI: 10.31128/AJGP-02-21-5840

Study information sourced from PubMed®, U.S. National Library of Medicine.

Medically Reviewed By

MMJ.com Medical Advisory Board

Last Updated: January 24, 2026

Important Information

Not Medical Advice: This research summary is for educational purposes only. It should not be used to diagnose, treat, cure, or prevent any disease or medical condition. Always consult a qualified healthcare provider before starting or changing any treatment.

Individual Variation: Research findings represent group averages. Your individual response to cannabis may differ based on genetics, other medications, underlying conditions, and many other factors.

Last reviewed: January 24, 2026

Important Notices

Research Summary Disclaimer

This content represents our interpretation of published scientific research for educational purposes. It should not be used to make treatment decisions without consulting a qualified healthcare provider. Individual results may vary from study findings.

FDA Notice

These statements have not been evaluated by the FDA. Cannabis is not intended to diagnose, treat, cure, or prevent any disease. The FDA has not approved cannabis for any medical condition except specific prescription medications.

Copyright & Fair Use

Research summaries are provided under fair use (17 U.S.C. § 107) for educational purposes. We provide brief summaries with attribution, not full reproductions. All studies remain the intellectual property of their respective authors and publishers.

Data Sources

Study information sourced from PubMed®, U.S. National Library of Medicine. Inclusion does not imply endorsement by NLM, NIH, or the federal government.

For complete information, see our Terms of Use and Research Content Policy.

FAQs: Cannabis for This Condition

Can I drive while using medical cannabis?

You should not drive for several hours or more after using cannabis. Cannabis impairs driving and increases crash risk. With oral products, impairment can last 8 hours or more. Plan transportation accordingly.

Does medical cannabis exempt me from DUI testing?

No. Having a medical cannabis prescription does not exempt you from roadside drug testing. You can test positive even when not feeling impaired, and medical necessity is generally not a legal defense.

How long should I wait to drive after using cannabis?

With oral cannabis products, impairment can last 8 hours or more. Smoked/vaped cannabis has shorter duration but still causes impairment. Avoid driving entirely during treatment initiation when effects are unpredictable.