What does cannabis research say about spasticity? We've analyzed 5 peer-reviewed studies to give you an honest, evidence-based overview.
Multiple high-quality studies support cannabis for this condition.
Study found evidence of effectiveness
Results varied by condition or dose
* Outcomes are based on our curated selection of research reviews. Individual study quality varies.
About This Research Summary: The information below aggregates findings from multiple peer-reviewed studies on cannabis and spasticity. This is for educational purposes only.
Research summaries are our interpretations of published studies. Individual responses to cannabis vary significantly. These findings do not guarantee similar results for any individual.
Study data sourced from PubMed®. Not evaluated by the FDA. See our Research Content Policy.
Cannabinoids are effective therapeutics for several medical indications if their specific pharmacological properties are considered. Different cannabinoids have different evidence levels for different conditions.
Nabiximols had a positive effect on spasticity symptoms in patients with motor neuron disease and had an acceptable safety and tolerability profile. This is the first positive proof-of-concept trial for cannabinoids in ALS spasticity.
There is reasonable evidence that cannabinoids improve nausea and vomiting after chemotherapy. They might improve spasticity. There is uncertainty about whether they improve pain, but if they do, it is neuropathic pain and the benefit is likely small. Adverse effects are very common.
There is conclusive or substantial evidence that cannabis or cannabinoids are effective for chronic pain in adults, chemotherapy-induced nausea and vomiting, and spasticity associated with multiple sclerosis. Evidence for most other conditions is limited, insufficient, or absent.
Smoked cannabis was superior to placebo in symptom and pain reduction in participants with treatment-resistant spasticity. Future studies should examine whether different doses can result in similar beneficial effects with less cognitive impact.
Our reviews are just a starting point. Browse thousands more studies on PubMed for spasticity.
Spasticity is a qualifying condition in many states. Our licensed physicians can evaluate whether medical cannabis is right for you.
Research Summary Disclaimer
This content represents our interpretation of published scientific research for educational purposes. It should not be used to make treatment decisions without consulting a qualified healthcare provider. Individual results may vary from study findings.
FDA Notice
These statements have not been evaluated by the FDA. Cannabis is not intended to diagnose, treat, cure, or prevent any disease. The FDA has not approved cannabis for any medical condition except specific prescription medications.
Copyright & Fair Use
Research summaries are provided under fair use (17 U.S.C. § 107) for educational purposes. We provide brief summaries with attribution, not full reproductions. All studies remain the intellectual property of their respective authors and publishers.
For complete information, see our Terms of Use and Research Content Policy.
