Over 53,000 cannabis studies exist on PubMed. We translate them into plain English so you can understand what the science actually says— without the medical jargon.
With over 53,000 cannabis studies published on PubMed, finding answers shouldn't require a medical degree. Our Research Library takes peer-reviewed studies and translates them into language patients can understand.
Each review explains what researchers studied, what they found, and most importantly—what it means for you. We're honest about limitations and always link to the original source so you can verify everything yourself.
Learn about our research methodology97% of patients agreed or strongly agreed that cannabis helped them decrease the amount of opioids they use, with 92% preferring cannabis over opioids for pain management.
Showing 75 research reviews
VER-01 (full-spectrum cannabis extract) shows potential as a new, safe and effective treatment for chronic low back pain.
Cannabis shows promise as a therapeutic option for Crohn's disease, demonstrating higher remission rates. However, quality of life was significantly better in the placebo group, highlighting the need for larger, standardized research studies.
In this landmark comparison of 90 trials with 22,028 patients, cannabis was found to be similarly effective to opioids for chronic pain relief, but with a critical advantage: patients on cannabis were 45% less likely to stop treatment due to adverse events compared to those on opioids.
In this rigorous 2024 trial, 150mg of nightly CBD was no better than placebo for most sleep measures in people with insomnia. While CBD users reported better well-being and showed slightly improved objective sleep efficiency, the primary sleep outcomes were not significantly different from placebo.
This 2024 systematic review of 15 studies found that most research shows 42-66% pain reduction with CBD or CBD+THC. However, 3 studies found no benefit, and the evidence overall is limited by small study numbers and varied methods.
These 2024 clinical practice guidelines, based on 70 studies, conclude that cannabis-based medicines show "moderate benefit" for chronic pain and also help related conditions like sleep problems and anxiety. The guidelines provide practical dosing and titration recommendations for clinicians.
THC significantly increases heart rate (~17 bpm), arterial stiffness, and reduces cardiac function—effects that could increase cardiovascular risk. CBD did NOT cause these cardiovascular effects. Smoking vs vaping THC made no difference.
Cannabinoids used for medical purposes in children and adolescents were associated with an increased risk of adverse events, including 3x higher withdrawal rates due to adverse events and nearly 2x higher serious adverse events compared to controls.
There was no benefit, perhaps worsened cognition and sleep, and there were many mild adverse events. The brief duration and strong placebo response limits interpretation of effects.
Clinicians should recommend against using cannabis or cannabinoids as a cancer-directed treatment unless within the context of a clinical trial. Cannabis may improve refractory chemotherapy-induced nausea and vomiting when added to standard antiemetics.
The study met both primary (GAD-7 and HAM-A scores) and secondary outcomes (CGI-I, CGI-S, PHQ-9 and PSQI scores). CBD significantly improved anxiety symptoms compared to placebo.
This comprehensive umbrella review of 101 meta-analyses found high-certainty evidence that CBD effectively reduces seizures in epilepsy, and cannabis-based medicines help chronic pain (30% pain reduction), MS spasticity, and IBD—but also identified clear risks during pregnancy, for mental health, and while driving.
If the research suggests cannabis might help your condition, our licensed physicians can evaluate whether you qualify for a medical marijuana card.
