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monoterpene

Linalool

Linalool

Pronounced: lin-AL-oh-ol

Linalool is a monoterpene terpene with a floral, lavender, sweet with spicy undertones aroma. It's also found naturally in Lavender, Coriander, Sweet basil. Research suggests linalool research supports calming and relaxation properties, though more human studies are needed.

Boiling Point

388°F (198°C)

Aroma

Floral

Also Found In

LavenderCorianderSweet basilBergamot

Aroma Profile:
Floral, lavender, sweet with spicy undertones

What is Linalool?

Linalool is the signature terpene of lavender and contributes to the floral, calming aroma of many cannabis strains. It's been used in traditional medicine for centuries and is one of the most extensively studied terpenes for its potential calming and stress-relieving properties.

How Linalool Works

Linalool modulates GABAergic transmission via benzodiazepine-responsive GABA-A receptors and enhances serotonin via 5-HT1A. Key finding: "Linalool odor has an anxiolytic effect without motor impairment in mice. The effect was mediated by GABAergic transmission via benzodiazepine-responsive GABA-A receptors" (Harada et al., 2018).

Researched Effects

Calming & Relaxation

Strong Evidence

Multiple human studies confirm lavender aromatherapy (rich in linalool) reduces anxiety markers and promotes relaxation.

✓ Compliant Language

Research supports calming and relaxation properties

✗ Avoid Saying

Treats anxiety disorders or is a sedative

Sleep Support

Moderate Evidence

Clinical studies show improved sleep quality with linalool-containing aromatherapy.

✓ Compliant Language

May promote restful sleep

✗ Avoid Saying

Cures insomnia or replaces sleep medication

Anti-inflammatory

Moderate Evidence

Preclinical research demonstrates anti-inflammatory mechanisms through multiple pathways.

✓ Compliant Language

Shows anti-inflammatory activity in research

✗ Avoid Saying

Reduces inflammation or treats inflammatory conditions

Understanding Evidence Levels

Strong EvidenceMultiple peer-reviewed clinical trials support this effect
Moderate EvidenceSupported by preclinical studies and limited clinical data
Emerging ResearchEarly research shows promise but more studies needed
Anecdotal ReportsBased on user reports; limited scientific research

Safety Information

Linalool is GRAS by the FDA and widely used in food and cosmetics. It's generally well-tolerated, though some individuals may experience skin sensitization with topical use.

Scientific References

Silexan, an orally administered Lavandula oil preparation

Kasper S, et al. • International Clinical Psychopharmacology (2010)

PubMed ID: 20512042

Clinical trial showing significant anxiety reduction with oral lavender oil.

Linalool Odor-Induced Anxiolytic Effects in Mice

Harada H, et al. • Frontiers in Behavioral Neuroscience (2018)

PubMed ID: 30405369

Key finding: Linalool has anxiolytic effect without motor impairment, mediated by GABAergic transmission via benzodiazepine-responsive GABA-A receptors.

Lavender and the Nervous System

Koulivand PH, et al. • Evidence-Based Complementary and Alternative Medicine (2013)

Comprehensive review of lavender/linalool effects on the nervous system.

Effect of lavender aromatherapy on sleep quality

Goel N, et al. • Sleep (2005)

PubMed ID: 16095700

Found improved sleep quality and morning alertness with lavender inhalation.

Anti-inflammatory activity of linalool

Peana AT, et al. • Phytomedicine (2002)

PubMed ID: 12587686

Demonstrated anti-inflammatory and analgesic properties in animal models.

Frequently Asked Questions

What is linalool?

Linalool is a floral-scented terpene abundant in lavender and found in many cannabis strains. It's one of the most studied terpenes for its calming and stress-relieving properties.

Does linalool help with anxiety?

Human clinical trials on lavender aromatherapy (rich in linalool) show significant reductions in anxiety markers. Research suggests it works through GABA receptors, similar to some anti-anxiety medications, but it's not a replacement for medical treatment.

Is linalool safe?

Yes, linalool is Generally Recognized as Safe (GRAS) by the FDA and is widely used in foods, cosmetics, and aromatherapy. It has an excellent safety profile with minimal side effects.

Quick Facts

Full Name
Linalool
Category
monoterpene
Boiling Point
388°F (198°C)
Aroma
Floral, lavender, sweet with spicy undertones
Strains High in Linalool
LavenderLA ConfidentialAmnesia HazeZkittlezDo-Si-Dos

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Educational Information

This content is for educational purposes only and is not medical advice. Consult a healthcare provider before using cannabis products.

Strain Variability

Terpene profiles vary significantly between batches, growers, and growing conditions—even for the same strain name. Always check lab test results.

Indica/Sativa Note

The indica/sativa distinction is largely marketing. Effects are better predicted by cannabinoid and terpene profiles than strain classification.