Bisabolol | Cannabis Terpene Guide
α-Bisabolol - Effects, Benefits & Strains
Pronounced: bih-SAB-oh-lol
Bisabolol is a sesquiterpene terpene with a delicate floral, sweet, chamomile-like aroma. It's also found naturally in Chamomile (German & Roman), Candeia tree. Research suggests bisabolol well-established skin-soothing and wound-healing properties, though more human studies are needed.
Boiling Point
307°F (153°C)
Aroma
Delicate floral
Also Found In
Aroma Profile:
Delicate floral, sweet, chamomile-like
Research Sources
4 peer-reviewed studies
Verified Via
PubMed / DOI
Evidence
Research-Backed
Updated
February 2026
What is Bisabolol?
α-Bisabolol is best known as the primary active component of chamomile and is highly valued in skincare for its soothing properties. Research shows gastroprotective effects, wound healing acceleration, and neuroprotective potential against amyloid-beta toxicity relevant to Alzheimer's disease.
How Bisabolol Works
Bisabolol shows anti-irritant and anti-inflammatory activity through multiple mechanisms including COX-2 and iNOS inhibition. It also enhances the absorption of other compounds through skin and mucous membranes (penetration enhancer). Research demonstrates significant gastroprotective effects via TRPV1 receptors.
Researched Effects
Skin Soothing & Wound Healing
Strong EvidenceExtensively researched in skincare; enhances wound healing with reduced scar formation.
✓ Compliant Language
Well-established skin-soothing and wound-healing properties
✗ Avoid Saying
Treats skin conditions
Gastroprotective
Moderate EvidenceSignificant gastroprotective effects mediated by TRPV1 receptors.
✓ Compliant Language
Research shows gastro-protective properties
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Treats ulcers
Sources
Anti-inflammatory
Moderate EvidenceDemonstrates anti-inflammatory activity through COX-2 and iNOS inhibition.
✓ Compliant Language
Research supports anti-inflammatory properties
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Reduces inflammation
Sources
Understanding Evidence Levels
Safety Information
Bisabolol is extremely well-tolerated and used extensively in sensitive-skin products and baby care. Excellent safety profile.
Frequently Asked Questions
What is bisabolol?
Bisabolol (α-bisabolol) is a gentle, floral terpene and the primary active component of chamomile. It's valued for its soothing properties in both cannabis and skincare.
Is bisabolol good for skin?
Yes! Bisabolol is extensively used in skincare, especially for sensitive skin, due to its well-documented anti-irritant properties. It's found in many baby care products.
Quick Facts
- Full Name
- α-Bisabolol
- Category
- sesquiterpene
- Boiling Point
- 307°F (153°C)
- Aroma
- Delicate floral, sweet, chamomile-like
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Educational Information
This content is for educational purposes only and is not medical advice. Consult a healthcare provider before using cannabis products.
Strain Variability
Terpene profiles vary significantly between batches, growers, and growing conditions—even for the same strain name. Always check lab test results.
Indica/Sativa Note
The indica/sativa distinction is largely marketing. Effects are better predicted by cannabinoid and terpene profiles than strain classification.