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Hybrid (Indica-leaning)

Triple Burger | Cannabis Strain Review & Effects

GMO x Double Burger

Triple Burger is a hybrid-leaning indica strain (GMO x Double Burger) with THC levels of 25-32%. It features a Beta-Caryophyllene-dominant terpene profile and is known for relaxed and happy. Best used during the evening.

THC

25-32%

CBD

0-1%

Best Time

Evening

Primary Effects

RelaxedHappyEuphoric

Flavor Notes

Earthy, Sweet, Herbal

Aroma

Earthy aroma with sweet and pungent notes

Research Sources

29 peer-reviewed studies

Verified Via

PubMed / DOI

Evidence

Research-Backed

Updated

December 2025

Every claim cites peer-reviewed research
How We Research

What is Triple Burger?

Triple Burger is a hybrid-leaning indica strain (GMO x Double Burger) with THC levels of 25-32%. It features a Beta-Caryophyllene-dominant terpene profile and is known for relaxed and happy. Best used during the evening.

About Triple Burger Strain

Triple Burger is a indica-dominant hybrid cannabis strain created by crossing GMO x Double Burger, bred by Skunk House Genetics. With THC levels ranging from 25% to 32%, Triple Burger is considered a high-potency strain that delivers powerful effects.

Users of Triple Burger commonly report feeling relaxed, happy, euphoric. The effects often start with a wave of mental relaxation that gradually spreads throughout the body. As the high deepens, physical tension melts away, making it ideal for unwinding after a long day. Best enjoyed in the evening, this strain helps transition from the day's activities into a more relaxed state.

Medical cannabis patients frequently turn to Triple Burger for relief from stress, anxiety, chronic pain. The caryophyllene content may provide anti-inflammatory and analgesic benefits, as this terpene interacts directly with CB2 receptors in the endocannabinoid system.

Due to its high potency, Triple Burger is best suited for experienced cannabis consumers. New users should approach with caution, starting with a very small dose and waiting to assess effects before consuming more. Common side effects may include dry mouth, dry eyes. Staying well-hydrated and having snacks on hand can help minimize discomfort.

The aroma of Triple Burger is characterized by earthy, sweet, pungent notes that create a distinctive sensory profile. On the palate, expect earthy, sweet, herbal flavors that develop throughout each session. The caryophyllene-dominant terpene profile is largely responsible for these aromatic and flavor characteristics, contributing to the entourage effect that shapes the overall experience.

Related Reading

Understanding Beta-Caryophyllene

Learn about this terpene

Browse All Strains

Compare Hybrid (Indica-leaning) strains

Cannabis for Stress

Qualifying conditions guide

Get Your MMJ Card

Access medical cannabis legally

Commonly Used For

Patients often seek Triple Burger for relief from the following conditions:

StressAnxietyChronic Pain

Note: These are commonly reported uses based on patient experiences. Individual results may vary. Always consult with a healthcare provider to determine if medical cannabis is appropriate for your specific condition.

Potential Side Effects

Be aware of these commonly reported side effects when using Triple Burger:

Dry MouthDry Eyes

How to minimize side effects

  • Start with a low dose, especially if new to cannabis
  • Stay hydrated before, during, and after use
  • Use in a comfortable, familiar environment
  • Avoid mixing with alcohol or other substances

Terpene Profile

Beta-Caryophyllenedominant
Spicy, peppery, woody, clove-like~0.8%

Primary research: Anti-inflammatory

Myrceneprimary
Earthy, musky, clove-like~0.4%

Primary research: Sedation & Relaxation

Limonenesecondary
Citrus, lemon, orange~0.2%

Primary research: THC Anxiety Reduction

Concentration Levels

Dominant (>1.0%)
Primary (0.5-1.0%)
Secondary (0.1-0.5%)
Trace (<0.1%)

Cannabinoid Profile

THCPsychoactive

25-32%

Pain Relief

CBD

0-1%

Seizure Reduction

Therapeutic Profile Matches

Based on Triple Burger's terpene and cannabinoid profile, it may be well-suited for these therapeutic applications:

migraines

73%
Good Match
  • High beta-caryophyllene content supports migraines & headaches
  • High myrcene content supports migraines & headaches
  • thc dominant ratio matches profile

nausea

67%
Good Match
  • High limonene content supports nausea & appetite loss
  • High beta-caryophyllene content supports nausea & appetite loss
  • thc dominant ratio matches profile

ptsd

63%
Moderate Match
  • High myrcene content supports ptsd & trauma
  • High beta-caryophyllene content supports ptsd & trauma
  • thc dominant ratio matches profile

muscle spasms

62%
Moderate Match
  • High myrcene content supports muscle spasms & spasticity
  • High beta-caryophyllene content supports muscle spasms & spasticity
  • Best used evening, aligning with condition needs

multiple sclerosis

60%
Moderate Match
  • High beta-caryophyllene content supports multiple sclerosis
  • High myrcene content supports multiple sclerosis
  • Best used evening, aligning with condition needs

Match scores are theoretical

These scores are based on terpene/cannabinoid research and do not guarantee specific effects. Individual responses vary significantly. Always consult a healthcare provider.

  1. 1

    Gertsch J, et al. β-Caryophyllene is a dietary cannabinoid Proceedings of the National Academy of Sciences. 2008

    Landmark paper: BCP directly activates CB2 receptors.

    PubMed: 18574142View Source
  2. 2

    Klauke AL, et al. The cannabinoid CB2 receptor-selective phytocannabinoid beta-caryophyllene exerts analgesic effects in mouse models of inflammatory and neuropathic pain European Journal of Pain. 2014

    Showed dual mechanism for neuropathic pain relief.

    PubMed: 24210682View Source
  3. 3

    Bahi A, et al. β-Caryophyllene, a CB2 receptor agonist produces multiple behavioral changes relevant to anxiety and depression in mice Physiology & Behavior. 2014

    BCP reduced anxiety via CB2 receptor activation.

    PubMed: 24930711View Source
  4. 4

    Horvath B, et al. β-Caryophyllene ameliorates cisplatin-induced nephrotoxicity in a cannabinoid 2 receptor-dependent manner Free Radical Biology and Medicine. 2012

    BCP reduced inflammation markers and oxidative stress.

    PubMed: 22326488View Source
  5. 5

    Tambe Y, et al. Gastric cytoprotection of the non-steroidal anti-inflammatory sesquiterpene, beta-caryophyllene Planta Medica. 1996

    BCP protected gastric mucosa in ulcer models.

    PubMed: 9005452View Source
  6. 6

    Surendran S, et al. Myrcene-What Are the Potential Health Benefits of This Flavouring and Aroma Agent? Frontiers in Nutrition. 2021

    Comprehensive review: β-myrcene may potentiate the anti-nociceptive properties of cannabinoids.

    PubMed: 34350208View Source
  7. 7

    Johnson MB, et al. The Effects of β-myrcene on Simulated Driving and Divided Attention: A Double-Blind, Placebo-Controlled, Crossover Pilot Study Cannabis. 2023

    Found myrcene alone did not significantly impair simulated driving performance.

    PubMed: 37287732View Source
  8. 8

    do Vale TG, et al. Central effects of citral, myrcene and limonene, constituents of essential oil chemotypes from Lippia alba (Mill.) n.e. Brown Phytomedicine. 2002

    Demonstrated dose-dependent sedative and motor-relaxant effects of myrcene in mice.

    PubMed: 12587690View Source
  9. 9

    Lorenzetti BB, et al. Myrcene mimics the peripheral analgesic activity of lemongrass tea Journal of Ethnopharmacology. 1991

    Found peripheral analgesic activity in animal models.

    PubMed: 1753786View Source
  10. 10

    Liktor-Busa E, et al. Analgesic Potential of Terpenes Derived from Cannabis sativa Pharmacological Reviews. 2021

    Comprehensive review of cannabis terpene analgesic effects including myrcene.

    PubMed: 34663685View Source
  11. 11

    Tagen M, et al. Vaporized D-limonene selectively mitigates the acute anxiogenic effects of Δ9-tetrahydrocannabinol Drug and Alcohol Dependence. 2024

    Johns Hopkins study showing limonene specifically reduces THC-induced anxiety in humans.

    PubMed: 38498958View Source
  12. 12

    Vieira AJ, et al. Limonene: Aroma of innovation in health and disease Chemico-Biological Interactions. 2018

    Comprehensive review of limonene's anxiolytic and antidepressant effects.

    PubMed: 29427589View Source
  13. 13

    Kiecolt-Glaser JK, et al. Olfactory influences on mood and autonomic, endocrine, and immune function Psychoneuroendocrinology. 2008

    Lemon scent exposure improved mood and reduced norepinephrine.

    PubMed: 18178322View Source
  14. 14

    Sun J. D-Limonene: safety and clinical applications Alternative Medicine Review. 2007

    D-limonene showed gastroprotective effects and clinical safety.

    PubMed: 18072821View Source
  15. 15

    Gaoni Y, Mechoulam R. Isolation, structure, and partial synthesis of an active constituent of hashish Journal of the American Chemical Society. 1964. doi:10.1021/ja01062a046

    Landmark paper first identifying and synthesizing THC.

    DOIView Source
  16. 16

    Whiting PF, et al. Cannabinoids for medical use: A systematic review and meta-analysis JAMA. 2015

    Comprehensive review finding moderate evidence for chronic pain.

    PubMed: 26103030View Source
  17. 17

    Aviram J, Samuelly-Leichtag G. Efficacy of Cannabis-Based Medicines for Pain Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Pain Physician. 2017

    Systematic review of clinical trials for neuropathic pain.

    PubMed: 28934780View Source
  18. 18

    Lutge EE, et al. The medical use of cannabis for reducing morbidity and mortality in patients with HIV/AIDS Cochrane Database of Systematic Reviews. 2013

    Systematic review of cannabis for HIV/AIDS symptoms including appetite.

    PubMed: 23633327View Source
  19. 19

    Smith LA, et al. Cannabinoids for nausea and vomiting in adults with cancer receiving chemotherapy Cochrane Database of Systematic Reviews. 2015

    High-quality evidence for CINV efficacy.

    PubMed: 26561338View Source
  20. 20

    Kesner AJ, Lovinger DM. Cannabinoids, Endocannabinoids and Sleep Frontiers in Molecular Neuroscience. 2020

    Review of THC effects on sleep architecture.

    PubMed: 32774241View Source
  21. 21

    Novotna A, et al. A randomized, double-blind, placebo-controlled, parallel-group, enriched-design study of nabiximols (Sativex), as add-on therapy, in subjects with refractory spasticity caused by multiple sclerosis European Journal of Neurology. 2011

    Phase III trial showing efficacy for MS spasticity.

    PubMed: 21362108View Source
  22. 22

    Silvestro S, et al. Molecular Targets of Cannabidiol in Experimental Models of Neurological Disease Molecules. 2020

    Comprehensive review of CBD's therapeutic applications and molecular targets.

    PubMed: 33171772View Source
  23. 23

    Thiele EA, et al. Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4): a randomised, double-blind, placebo-controlled phase 3 trial Lancet. 2018

    Phase III trial leading to FDA approval of Epidiolex.

    PubMed: 29395273View Source
  24. 24

    Devinsky O, et al. Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial Lancet Neurology. 2016

    Open-label trial showing 36.5% reduction in seizures.

    PubMed: 26724101View Source
  25. 25

    Shannon S, et al. Cannabidiol in anxiety and sleep: A large case series Permanente Journal. 2019

    79.2% of patients reported reduced anxiety within first month.

    PubMed: 30624194View Source
  26. 26

    Bergamaschi MM, et al. Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients Neuropsychopharmacology. 2011

    CBD reduced anxiety in simulated public speaking test.

    PubMed: 21307846View Source
  27. 27

    Burstein S. Cannabidiol (CBD) and its analogs: a review of their effects on inflammation Bioorganic & Medicinal Chemistry. 2015

    Review of CBD's anti-inflammatory mechanisms.

    PubMed: 25703248View Source
  28. 28

    Shannon S, et al. Cannabidiol in Anxiety and Sleep: A Large Case Series Permanente Journal. 2019

    66.7% of patients reported improved sleep in this anxiety and sleep study.

    PubMed: 30624194View Source
  29. 29

    Urits I, et al. Use of cannabidiol (CBD) for the treatment of chronic pain Best Practice & Research Clinical Anaesthesiology. 2020

    Comprehensive review of CBD for chronic pain management.

    PubMed: 33004159View Source

Research Verification

All citations link directly to PubMed or the original source. You can verify any claim by clicking the reference link. Learn more about how we research.

Frequently Asked Questions

What are the effects of Triple Burger?

Triple Burger is known for producing relaxed, happy, euphoric effects. As a hybrid indica, it's typically best suited for evening use.

What conditions might Triple Burger help with?

Triple Burger is commonly used by patients seeking relief from stress, anxiety, chronic pain. Always consult with a healthcare provider before using cannabis for medical purposes.

How strong is Triple Burger?

Triple Burger is considered a high-potency strain with THC levels typically ranging from 25-32%. New users should approach with caution and start with a low dose.

What does Triple Burger taste and smell like?

Triple Burger features earthy, sweet, herbal flavors with a earthy, sweet, pungent aroma. Its unique terpene combination creates a memorable sensory experience.

What are the side effects of Triple Burger?

Common side effects include dry mouth, dry eyes. Staying hydrated and starting with a low dose can help minimize these effects.

Quick Facts

Type
Hybrid (Indica-leaning)
Genetics
GMO x Double Burger
Breeder
Skunk House Genetics
Genetic Family
GMO/Garlic Family
Best Time of Use
Evening
Availability
moderate
Grow Difficulty
moderate
Experience Level
Experienced Users

Dominant Terpene

Beta-Caryophyllene

Spicy, peppery, woody, clove-like

Want to try Triple Burger? Get your medical marijuana card today.

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Related by Genetics

Garlicane

hybrid indica

Educational Information

This content is for educational purposes only and is not medical advice. Consult a healthcare provider before using cannabis products.

Strain Variability

Profiles vary between batches, growers, and growing conditions. Always check lab test results for the specific product you're purchasing.

Beyond Indica/Sativa

Effects are better predicted by cannabinoid and terpene profiles than strain classification. Focus on the chemistry, not the label.

Understanding Therapeutic Profiles

Learn how terpenes and cannabinoids work together to create each strain's unique effects and therapeutic potential through the entourage effect.

Learn About Therapeutic Profiles