Delta-8 THC (Delta-8-Tetrahydrocannabinol) | Cannabinoid Guide
Complete Guide to Delta-8 THC in Medical Cannabis
Pronounced: DEL-tuh-eight tee-aych-SEE
Delta-8 THC (Delta-8-Tetrahydrocannabinol) is a psychoactive minor cannabinoid. Everything you need to know about delta-8 THC. Learn how it differs from delta-9, its effects, legal status, and safety concerns..
Boiling Point
347°F (175°C)
Formula
C₂₁H₃₀O₂
Legal Status
Federally legal gray area (hemp-derived); banned in some states
May cause impairment. Do not drive or operate machinery after use.
Research Sources
4 peer-reviewed studies
Verified Via
PubMed / DOI
Evidence
Research-Backed
Updated
February 2026
What is Delta-8 THC?
Delta-8 THC is an isomer of delta-9 THC with the double bond at carbon 8 instead of carbon 9. It occurs naturally in trace amounts but commercial products are semi-synthetically derived from CBD. User surveys report 71% experience relaxation, 68% euphoria, with fewer adverse effects than delta-9 THC. Users often describe it as "THC's nicer younger sibling."
How Delta-8 THC Works
Delta-8 binds to CB1 receptors similarly to delta-9 THC but with lower affinity—approximately 50-67% as potent based on receptor binding studies. This may explain the reportedly milder high and reduced anxiety compared to delta-9 in some users.
Researched Effects
Mild Psychoactivity
Emerging ResearchProduces a high similar to delta-9 THC but typically described as milder.
✓ Compliant Language
Produces psychoactive effects similar to but milder than THC
✗ Avoid Saying
Safe alternative to THC
Sources
Anti-nausea
Moderate EvidenceEarly clinical studies showed efficacy in pediatric cancer patients.
✓ Compliant Language
Research suggests anti-nausea properties
✗ Avoid Saying
Treats nausea
Sources
Appetite Stimulation
Emerging ResearchAnimal studies show appetite stimulation effects.
✓ Compliant Language
May stimulate appetite
✗ Avoid Saying
FDA-approved appetite aid
Sources
Dosing Guidance
Start with 5-10mg for beginners. Effects are roughly 50-75% as potent as delta-9 THC, but individual responses vary. Wait 2+ hours before redosing with edibles.
Safety Information
FDA WARNING: Delta-8 products have significant safety concerns. Production quality varies—many products contain residual solvents, heavy metals, or inaccurate labeling. Products often lack third-party testing. Delta-8 is psychoactive and can cause impairment. Not recommended for pregnant women or those under 21. Banned or restricted in many states.
Potential Side Effects
- Psychoactive effects (milder than delta-9)
- Dry mouth and red eyes
- Impaired coordination
- Increased heart rate
- Possible anxiety (less common than delta-9)
- Product quality concerns (contaminants, solvents)
Drug Interactions
Similar to delta-9 THC. May interact with sedatives and other medications.
Frequently Asked Questions
What is delta-8 THC?
Delta-8 THC is an isomer of delta-9 THC that produces similar but reportedly milder psychoactive effects. It's typically made by converting CBD from hemp.
Is delta-8 THC legal?
It exists in a legal gray area federally. The 2018 Farm Bill legalized hemp derivatives, but some argue delta-8 is a synthetic. Many states have explicitly banned it.
How does delta-8 compare to delta-9 THC?
Delta-8 is estimated to be 50-75% as potent as delta-9. Users often describe it as "THC lite" with similar effects but less anxiety and paranoia. However, quality control issues are common.
Quick Facts
- Full Name
- Delta-8-Tetrahydrocannabinol
- Category
- minor Cannabinoid
- Psychoactive
- Yes
- Boiling Point
- 347°F (175°C)
- Formula
- C₂₁H₃₀O₂
Want to explore Delta-8 THC products? Get your medical marijuana card today.
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Medical Disclaimer
This content is for educational purposes only and is not medical advice. Consult a healthcare provider before using cannabis products.
Individual Variation
Cannabis affects everyone differently based on genetics, tolerance, and other factors. What works for one person may not work for another.
Start Low, Go Slow
Always begin with the lowest effective dose and increase gradually to minimize risk of adverse effects.