Texas Qualifying Conditions: Detailed Guide
What conditions qualify for medical marijuana in Texas?
Texas approves medical marijuana (low-THC cannabis) for more than a dozen qualifying conditions including epilepsy, PTSD, cancer, multiple sclerosis, autism, chronic pain, traumatic brain injury, and Crohn's disease. The Texas Compassionate Use Program (TCUP) has expanded significantly since 2015, most recently under HB 46 of 2025 (effective September 1, 2025), and now serves over 100,000 patients. MMJ.com offers telehealth evaluations for $149.99 with same-day certification.## What is the complete list of Texas qualifying conditions?
The Texas Compassionate Use Program (TCUP) recognizes the following qualifying conditions under Tex. Occ. Code § 169.003 for 2026:
Neurological Conditions
- [Epilepsy and Seizure Disorders](/texas-medical-marijuana-card/qualifying-conditions/epilepsy/) (including refractory epilepsy)
- Multiple Sclerosis (MS)
- Amyotrophic Lateral Sclerosis (ALS)
- Spasticity Disorders (from brain injuries or disease)
- Incurable Neurodegenerative Diseases (Parkinson's, Alzheimer's, Huntington's, Lewy body dementia, and similar conditions)
- Traumatic Brain Injury (TBI) (added by HB 46 of 2025)
Mental Health Conditions
- Post-Traumatic Stress Disorder (PTSD)
Developmental Conditions
Cancer
- Cancer (all cancer patients now qualify, previously limited to terminal diagnosis)
Pain and Digestive Conditions (added by HB 46 of 2025)
- Chronic Pain (a condition that causes chronic pain, associated with a documented underlying condition)
- Crohn's Disease and Other Inflammatory Bowel Disease (IBD)
End-of-Life Care (added by HB 46 of 2025)
- Terminal Illness
- Conditions for which the patient is receiving hospice or palliative care
Note: Conditions like anxiety (as a standalone diagnosis), migraines, and glaucoma do not currently qualify. Chronic pain, TBI, Crohn's / IBD, and hospice / palliative care qualify as of September 1, 2025 under HB 46.
About the Qualifying Medical Conditions
Below is information about each qualifying condition and the research that informed Texas' decision to include it in the Compassionate Use Program.
Epilepsy and Seizure Disorders
Epilepsy and seizure disorders are approved qualifying conditions under the Texas Compassionate Use Program. Texas originally created TCUP based on clinical trial research examining CBD in patients with treatment-resistant epilepsy.
PTSD
PTSD is an approved qualifying condition under the Texas Compassionate Use Program. Texas included this condition based on research examining cannabinoid use among patients with PTSD.
Chronic Pain
A condition that causes chronic pain is an approved qualifying condition under the Texas Compassionate Use Program, added by HB 46 of 2025. The certifying physician documents the underlying condition producing the pain; Texas framed the addition in part as an alternative to opioid prescribing.
Multiple Sclerosis
MS is an approved qualifying condition under the Texas Compassionate Use Program. Texas included this condition based on clinical research examining cannabinoid use in patients with MS-related spasticity.
Cancer
Cancer is an approved qualifying condition under the Texas Compassionate Use Program. Texas included this condition based on research examining cannabinoid use among cancer patients experiencing treatment-related symptoms.
Autism Spectrum Disorder
Autism Spectrum Disorder is an approved qualifying condition under the Texas Compassionate Use Program. Texas included this condition based on research examining cannabis use among patients with autism spectrum disorder.
ALS
ALS is an approved qualifying condition under the Texas Compassionate Use Program. Texas included this condition based on research surveying ALS patients about symptom management.
Traumatic Brain Injury
Traumatic brain injury (TBI) is an approved qualifying condition under the Texas Compassionate Use Program, added by HB 46 of 2025. Documentation typically comes from neurology, rehabilitation, or VA records establishing the injury.
Crohn's Disease and Inflammatory Bowel Disease
Crohn's disease and other forms of inflammatory bowel disease (IBD) are approved qualifying conditions under the Texas Compassionate Use Program, added by HB 46 of 2025. Gastroenterology records documenting the diagnosis support the prescription.
Terminal Illness and Hospice or Palliative Care
A terminal illness, or any condition for which the patient is receiving hospice or palliative care, qualifies under the Texas Compassionate Use Program as of HB 46 of 2025.
Spasticity Disorders
Spasticity disorders from brain injuries or disease are approved qualifying conditions under the Texas Compassionate Use Program as determined by the Texas Legislature.
What conditions might be added in the future?
Texas legislators continue to discuss expanding TCUP. Conditions that have been proposed in past sessions but are not currently covered include:
- Glaucoma
- Sickle cell disease
- Anxiety and other mood disorders
Medical Disclaimer
This page provides information about Texas' qualifying conditions for the Compassionate Use Program. The inclusion of a condition in Texas' program does not constitute medical advice or a guarantee of therapeutic benefit. Individual results vary. Potential side effects may include dizziness, sedation, and cognitive changes. Always consult a healthcare provider before starting treatment.
Reviewed by MMJ.com Medical Advisory Team Content verified August 2026